Molecular Barriers to Zoonotic Transmission of Prions

The risks posed to human health Water Bottle by individual animal prion diseases cannot be determined a priori and are difficult to address empirically.The fundamental event in prion disease pathogenesis is thought to be the seeded conversion of normal prion protein to its pathologic isoform.We used a rapid molecular conversion assay (protein misfo

read more

A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction.

Dysregulation of the stress response is implicated in drug addiction; therefore, polymorphisms in stress-related genes may be involved in this disease.An analysis was performed to identify associations between variants in 11 stress-related genes, selected a priori, and heroin addiction.Two discovery samples of American subjects of European descent

read more

A Cross-sectional Study to Assess Insulin Resistance and Atherogenic Index of Plasma as Predictors of Risk of Cardiometabolic Disease among Undergraduate Medical Students at a Tertiary Care Teaching Hospital, Karnataka

Background: Medical profession is known for stress and challenges due to hectic academic schedules which makes students, high-risk candidates for diabetes mellitus, hypertension and cardiometabolic disease (CMD).Surrogate markers such as homeostatic model assessment insulin resistance (HOMA-IR) and atherogenic index of plasma (AIP) along with routi

read more